Portable Laser-Operated Counterfeit Drug Identifier (CoDI) for Tablets


Counterfeit drugs (also known as “fake or falsified medicines”) have become a major world-wide public health concern. Falsified medicines may contain toxic substances, the wrong active ingredients, suboptimal amounts of active ingredients, or no active ingredients at all. CDC researchers developed a portable (handheld), battery-operated, and relatively inexpensive device that non-trained personnel can use quickly to evaluate a particular branded tablet for authenticity. The low-cost and simple-to-use CoDI can aid the general public as well as hospitals, clinics, and pharmacies to assess drug quality. The CoDI does not require the use of consumables such as solvents or chemicals, and does not destroy the sample. Thus, the device is safe to use and allows the samples to be available for subsequent analysis if necessary. The CoDI can benefit drug regulatory, Customs and law enforcement agencies for testing and screening large amounts of samples. CoDI provides instantaneous results that can allow agencies to rapidly begin searching for counterfeit drug sources and implement intervening measures to stem the production and availability of counterfeit drugs. CDC researchers successfully tested the CoDI prototype in Ghana on a project to detect falsified, degraded, and expired ingredients in antimalarial tablets. Field trials to test additional drug samples are underway. Matchbook sized versions with yes/no indicator lights are being developed for specific brands. These are even simpler to use and lessen any chance of operator error.

Potential Commercial Applications: Competitive Advantages:
  • Instrument can detect counterfeit, degraded, and expired drugs in tablet formation
  • The general public as well as hospitals, clinics, and pharmacies can assess drug quality
  • Drug regulatory, Customs and law enforcement agencies may test and screen large amounts of samples
  • Pharmaceutical companies may use the device for quality control purposes or generic drug testing
 
  • Simple, efficient, and quick detection of counterfeit and poor quality drugs
  • CoDI uses inexpensive laser technology versus other analytical equipment
  • Does not destroy sample
  • First field trials to test antimalarial drug samples with the device in Ghana were successful
  • Field trials to test additional drug samples are underway


Related Invention(s):
E-161-2013/0


Inventors:

Michael Green (CDC)  ➽ more inventions...


Intellectual Property:
US Application No. 62/287,711
PCT Application No. PCT/US2017/015324

Publications:
Yong YL, et al PMID 25897069
Green MD, et al. PMID 25897066

Collaboration Opportunity:

The CDC Technology Transfer Office (TTO) is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize: Portable Laser-Operated Counterfeit Drug Identifier (CoDI). For collaboration opportunities, please contact CDC TTO at tto@cdc.gov or 1-404-639-1330 .


Licensing Contact:
Jeremiah Mitzelfelt,
Email: jeremiah.mitzelfelt@nih.gov
Phone: 301-443-8518

OTT Reference No: E-572-2013/1
Updated: Jan 17, 2018