Rabbit Antibody to Mouse Sphingosine kinase 2 (SphK2)


Two isoforms of sphingosine kinase, sphingosine kinase 1 (SphK1) and sphingosine kinase 2 (SphK2), convert sphingosine to sphingosine 1-phosphate (S1P) in mammalian cells. While the importance of SphK1 has been known for some time, information about SphK2 is still being revealed. Therefore, researchers at NIH have developed an antibody against mouse SphK2, which can be used to further understand the role of this enzyme.

Potential Commercial Applications: Competitive Advantages:
The antibody can be used to detect and measure SphK2. The antibody works very well for western blotting.


Development Stage:
In vitro data available

Inventors:

Richard Proia (NIDDK)  ➽ more inventions...


Intellectual Property:
Research Tool – Patent protection is not being pursued for this technology.

Publications:
Olivera A, et al. PMID 16316995

Licensing Contact:
Mythreyi Shastri, Ph.D.
Email: shastrim@mail.nih.gov
Phone: 301-435-0613

OTT Reference No: E-466-2013-0
Updated: Aug 6, 2013