Human Influenza Virus Real-time RT-PCR Detection and Characterization Panel

This invention relates to methods of rapidly detecting influenza, including differentiating between type and subtype. Unlike culture and serological tests requiring 5 to 14 days for completion, CDC researchers developed a rapid, accurate assay, which is easily adapted to kit form. This assay also requires less labor input than immunoassays. These methods can be used to quickly identify a broad variety of influenza types and subtypes, including viruses that may be involved in pandemics (such as H5N1, for example).

Potential Commercial Applications: Competitive Advantages:
  • Influenza diagnostic using clinical specimens
  • High-throughput screenings
  • Influenza surveillance programs
  • Already FDA approved
  • Especially useful for H5N1 screening
  • Sensitive detection
  • Specific discrimination of influenza subtypes
  • Easily formatted as kit or array
  • Faster than culturing and serological identification methods
  • Less laborious and more objective than immunoassays

Development Stage:
In vitro data available


Stephen Lindstrom (CDC)  ➽ more inventions...

Alexander Klimov (CDC)  ➽ more inventions...

Nancy Cox (CDC)  ➽ more inventions...

Lamorris Loftin (CDC)  ➽ more inventions...

Intellectual Property:
US Pat: 8,241,853 issued 2012-08-14
PCT Pat: 8,568,981 issued 2013-10-29
US Pat: 9,382,592 issued 2016-07-05
US Pat: 10,036,076 issued 2018-07-31
US Pat: 10,196,699 issued 2019-02-05
US Application No. 15/182,852 filed on 2016-06-15
US Application No. 16/042,061 filed on 2018-07-23
Various international filings pending

Jernigan DB, et al. PMID 21342897

Licensing Contact:
Karen Surabian, J.D., M.B.A.
Phone: 301-594-9719

OTT Reference No: E-331-2013-0
Updated: Dec 4, 2013