Regulation of ATG7 Beclin 1 Program of Autophagic Cell Death by Caspase-8

The invention discloses the role of autophagy in regulation cell death. Further it teaches a method of inducing autophagic cell death by administering a caspase inhibitor. The invention also discloses that autophagic cell death can be induced by caspase-8 inhibition and requires the genes ATG7 and Beclin 1.

Inventors:

Michael Lenardo (NIAID)  ➽ more inventions...


Intellectual Property:
US Application No. 11/119,569

Licensing Contact:
Yogikala Prabhu,
Email: prabhuyo@niaid.nih.gov
Phone: 301-761-7789

OTT Reference No: E-318-2004-0
Updated: May 24, 2016