Simple and Rapid Loop-Mediated Isothermal Amplification (LAMP)-based Assay for Mycoplasma pneumoniae Detection
Mycoplasma pneumoniae (M. pneumonia) can cause several different types of infection including chest colds and pneumonia. M. pneumoniae is a leading cause of community-acquired pneumonia. People of all ages are at risk for getting M. pneumonia infection, but it is most common among young adults and school-aged children. Current methods of detecting this agent are laborious and time consuming, so testing is not usually performed. However, knowing whether someone has M. pneumoniae infection is important for choosing the right antibiotic for treatment. Although real-time PCR assays exist for detecting this pathogen, they require sophisticated and expensive machinery as well as specialized technical expertise. CDC researchers have developed a simple loop-mediated isothermal amplification (LAMP)-based assay to detect this pathogen. This method only requires a simple heat block and is an easy-to-read colorimetric assay. The technology is simple to perform and can be a rapid point-of-care kit. It is ideal for use in resource-limited laboratories, hospitals, clinics, and community settings.
Potential Commercial Applications: | Competitive Advantages: |
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Related Invention(s):
E-108-1989-0
E-125-1992-0
E-300-2013-0
Inventors:
Jonas Winchell (CDC) ➽ more inventions...
Brianna Petrone (CDC) ➽ more inventions...
Maureen Diaz (CDC) ➽ more inventions...
Bernard Wolff (CDC) ➽ more inventions...
Alexandra DeLaney (CDC) ➽ more inventions...
Intellectual Property:
U.S. Pat: 10,233,504 issued 2019-03-19
US Application No. 15/043,194
Publications:
Petrone BL, et al. PMID 26179304
Collaboration Opportunity:
The CDC Technology Transfer Office (TTO) is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize: Simple and Rapid Loop-Mediated Isothermal Amplification (LAMP)-based Assay for Mycoplasma pneumoniae Detection. For collaboration opportunities, please contact CDC TTO at tto@cdc.govor 1-404-639-1330.
Licensing Contact:
Karen Surabian, J.D., M.B.A.
Email: karen.surabian@nih.gov
Phone: 301-594-9719
OTT Reference No: E-269-2014-0
Updated: Jun 22, 2018