Polyclonal Antibodies to the Kidney Protein Urea Transporter 1 (UTA1)


Antibodies to UTA1, useful for immunoblotting and immunocytochemistry, are available to resell for research purposes. Urea Transporter 1 (UTA1) is activated by vasopressin and is responsible for urea transport across the apical membrane into the intracellular space within the renal inner medullary collecting duct. The inventor has developed rabbit polyclonal antibodies directed against a peptide sequence in human UTA1. Antibody also recognizes UTA3, another product of the same gene.

Potential Commercial Applications: Competitive Advantages:
Western blotting and immunocytochemistry 


Inventors:

Mark Knepper (NHLBI)  ➽ more inventions...


Intellectual Property:
Research Tool -- patent protection is not being pursued for this technology

Publications:
S Nielsen, J Terris, CP Smith, MA Hediger, CA Ecelbarger, MA Knepper. Cellular and subcellular localization of the vasopressin-regulated urea transporter in rat kidney. Proc Natl Acad Sci USA. 1996 May 28;93(11):5495-5500. PubMed abs

Licensing Contact:
Michael Shmilovich, J.D.
Email: shmilovm@mail.nih.gov
Phone: 301-435-5019

OTT Reference No: E-268-2008-0
Updated: May 5, 2009