Superresolution Microscopy via Azicon Beam Polarization Devices

The technology offered for licensing pertains to novel polarizers that produce tangentially and radially polarized beams. The polarizers and polarizing beam splitter of the technology include one or more pairs of axicons (also known as conical lenses) that are configured to separate an input beam into a radially polarized component and a tangentially (or azimuthally) polarized component. A second axicon pair can be positioned to recombine the tangentially polarized component so as to provide a more uniform beam intensity. The radial polarized component can be reflected or otherwise directed so that one or both the radial and tangential components are available for use.

Potential Commercial Applications: Competitive Advantages:
The disclosed methods and apparatus of the technology can be used to provide radially or tangentially polarized beams (or both) to many applications. In particular the technology can be effectively utilized in applications such as:
  • Multi-photon microscopy
  • Microlithography
  • Ultrafine imaging in conjunction with the use of fluorophores
 The technology provides higher optical resolution for certain applications as compared with currently used methodologies.

Development Stage:
The invention is fully developed.


Jay Knutson (NHLBI)  ➽ more inventions...

Intellectual Property:
US Pat: 9,086,509 issued 2015-07-21
PCT Application No. PCT/US2011/025755 filed on 2011-02-22
US Application No. 13/581,107 filed on 2012-08-24

Collaboration Opportunity:

The NHLBI Laboratory of Molecular Biophysics is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize this technology. Please contact Brian Bailey at 301-594-4094 for more information.

Licensing Contact:
Michael Shmilovich, J.D.
Phone: 301-435-5019

OTT Reference No: E-251-2009-0
Updated: Aug 31, 2010