Method Of Identifying Inhibitors Of The Jak-STAT Signal Transduction Pathway


The invention provides identification methods for agents which inhibit the Jak-STAT signaling transduction pathway. Drugs identified by these methods are candidates for the treatment of proliferative disorders dependent on the Jak-STAT pathway, including those caused by HTLV-1. In addition, such agents may be potent immunosuppressive drugs with potential applications not only for organ transplantation but also for treatment of autoimmune diseases.

Inventors:

Warren Leonard (NHLBI)  ➽ more inventions...


Intellectual Property:
U.S. Pat: 6,265,160 issued 2001-07-24
US Application No. PCT/US96/011206

Licensing Contact:
Michael Shmilovich, J.D.
Email: shmilovm@mail.nih.gov
Phone: 301-435-5019

OTT Reference No: E-176-1995-0
Updated: Apr 1, 1996