Antigen, Encoding Gene, Related Monoclonal Antibody and Hybridoma Clones for Streptococcus pneumoniae Serological Diagnostics
This CDC developed invention pertains to Streptococcus pneumoniae protein "pneumococcal fimbrial protein A (PfpA)," as well as the encoding pfpA gene. S. pneumoniae linked pneumococcal disease is prevalent among the very young, the elderly and also immunocompromised individuals. This invention covers the breadth of directly PfpA-related technology that might be employed for development of diagnostic tests for S. pneumoniae and/or vaccines directed against the pathogen. In addition to the the intellectual property protected amino acid sequence and encoding plasmid, monoclonal antibodies and corresponding hybridomas are also available.
Potential Commercial Applications: | Competitive Advantages: |
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Development Stage:
In vitro data available
Related Invention(s):
E-030-2010-0
E-250-2013-0
E-325-2013-0
Inventors:
Harold Russell (CDC) ➽ more inventions...
Jacquelyn Sampson (CDC) ➽ more inventions...
Steven O'connor (CDC) ➽ more inventions...
Intellectual Property:
U.S. Pat: 6,312,944 issued 2001-11-06
U.S. Pat: 5,422,427 issued 1995-06-06
Publications:
Russell H, et al. PMID 2229341
Sampson JS, et al. PMID 7505262
Licensing Contact:
Karen Surabian, J.D., M.B.A.
Email: karen.surabian@nih.gov
Phone: 301-594-9719
OTT Reference No: E-157-1991-0
Updated: Jan 20, 2014