Regenerative Therapy for Cartilage Damage
The subject technology discloses a tissue engineering method for treating cartilage damage. Stem cells from bone marrow are attached to a novel scaffold, hyaluronic acid-coated fibrin microbeads, and transferred to a live host to form cartilage. The regenerated cartilage is stable and not hypertrophic, which has been problematic in the current regenerative methods.
Potential Commercial Applications: | Competitive Advantages: |
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Inventors:
Pamela Robey (NIDCR) ➽ more inventions...
Mitchell Shirvan
Rafael Gorodetsky
Sergei Kuznetsov (NIDCR) ➽ more inventions...
Astar Lazmi-Hailu
Intellectual Property:
US Application No. 62/513,874
PCT Application No. PCT/US2018/035448
US Application No. 16/616,418
Collaboration Opportunity:
The National Institute of Dental and Craniofacial Research is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize the novel methods for cartilage repair. For collaboration opportunities, please contact David Bradley, Ph.D. at bradleyda@nidcr.nih.gov.
Licensing Contact:
Vladimir Knezevic, M.D.
Email: vlado.knezevic@nih.gov
Phone: 301.443.5560
OTT Reference No: E-152-2017-0
Updated: Jan 25, 2018