HCV/BVDV Chimeric Genomes and Uses Thereof

The current invention provides nucleic acid sequences comprising chimeric viral genome of hepatitis C Virus (HCV) and bovine viral diarrhea viruses (BVDV). The chimeric viruses are produced by replacing the structural region or a structural gene of an infectious BVDV clone with the corresponding region or gene of an infectious HCV. It covers the use of these sequences and polypeptides encoded by all or part of the sequences in the development of vaccines and diagnostic assays for HCV and the development of screening assays for the identification of antiviral agents for HCV.

Related Invention(s):


Jens Bukh (NIAID)  ➽ more inventions...

Suzanne Emerson (NIAID)  ➽ more inventions...

Robert Purcell (NIAID)  ➽ more inventions...

Jae-hwan Nam (NIAID)  ➽ more inventions...

Intellectual Property:
US Pat: 7,009,044 issued 2006-03-07
PCT Application No. 60/137,817 filed on 1999-06-04

Licensing Contact:
Peter Soukas, J.D.
Email: peter.soukas@nih.gov
Phone: 301-496-2644

OTT Reference No: E-102-1999-0
Updated: Jul 6, 2020