Cloned Genome of Infectious Hepatitis C Virus of Genotype 2a and Uses Thereof


The current invention provides a nucleic acid sequence comprising the genome of infectious hepatitis C viruses (HCV) of genotype 2a. The encoded polyprotein differs from those of the infectious clones of genotypes 1a and 1b (U.S. Patent 6,153,421) by approximately thirty (30) percent. It covers the use of this sequence and polypeptides encoded by all or part of the sequence, in the development of vaccines and diagnostic assays for HCV and the development of screening assays for the identification of antiviral agents for HCV. Additional information can be found in Yanagi et al. (1999), Virology 262, 250-263.

Related Invention(s):
E-050-1998-0
E-102-1999-0
E-173-1999-0


Inventors:

Masayuki Yanagi (NIAID)  ➽ more inventions...

Jens Bukh (NIAID)  ➽ more inventions...

Suzanne Emerson (NIAID)  ➽ more inventions...

Robert Purcell (NIAID)  ➽ more inventions...


Intellectual Property:
US Pat: 7,084,266 issued 2006-08-01
US Application No. PCT/US00/15446 filed on 2000-06-02
PCT Application No. 60/137,693 filed on 1999-06-04

Licensing Contact:
Peter Soukas, J.D.
Email: peter.soukas@nih.gov
Phone: 301-496-2644

OTT Reference No: E-100-1999-0
Updated: Jul 6, 2020