Plasmodium vivax and Plasmodium knowlesi Duffy Receptor


A useful protein in the development of a potential malaria vaccine has been developed by cloning the gene for the Duffy binding receptor of Plasmodium vivax, a human malaria. Duffy blood group determinants on human erythrocytes are known to be essential for invasion by both the P. vivax and P. knowlesi malaria strains. A candidate malaria vaccine could result from the use of antibodies to the recombinant Duffy receptor binding protein or the receptor protein itself functioning through competitive blocking therapy.

Inventors:

Louis Miller (NIAID)  ➽ more inventions...


Intellectual Property:
U.S. Pat: 5,198,347 issued 1993-03-30
U.S. Pat: 5,541,292 issued 1996-07-30

Licensing Contact:
Peter Tung, Ph.D., M.B.A.
Email: peter.tung@nih.gov
Phone: 240-669-5483

OTT Reference No: E-090-1990-0
Updated: Feb 28, 2011