Implantable Medical Devices with Electric Current Retrieval Assist


Implantable devices, such as filters and stents, typically include structures that anchor to surrounding tissue. To prevent blood clots from reaching the heart, an IVC filter may be implanted into the patient. While generally effective at preventing movement of post-implantation, traditional anchors present challenges when attempting to remove the device from the subject. In particular, the tissue to which the device is anchored may grow around the anchors making removal difficult. The invention pertains to an implantable device (e.g., an IVC filter) with a plurality of expandable members each having a portion that comes into contact with the tissue of a subject when expanded. A force is then provided to the retrieval portion to collapse the implantable device. An electrical current (approx. 0.2 and 0.55 Amps) is also provided to the portions of the expandable members that come into contact with the tissue of the subject via the retrieval apparatus by way of a conductive snare in one or more of the expandable members.

Potential Commercial Applications: Competitive Advantages:
  • Blood clot prevention
  • Stent removal
  • Implantation
 
  • Ease of removal from subject tissue


Development Stage:
  • Early-stage
  • In vitro data available
  • In vivo data available (animal)


Related Invention(s):
E-244-2000/1


Inventors:

Bradford Wood (CC)  ➽ more inventions...

Ayele Negussie (CC)  ➽ more inventions...

Hayet Amalou (CC)  ➽ more inventions...

Sheng Xu (CC)  ➽ more inventions...


Intellectual Property:
US Application No. 15/127,974
US Application No. 61/968,757
PCT Application No. PCT/US2015/022002

Publications:
Amalou H, et al. PMID 24745908

Collaboration Opportunity:

The National Institutes of Health Clinical Center is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize conduction assisted stent removal. For collaboration opportunities, please contact Ken Rose, Ph.D., JD at rosek@mail.nih.gov or 240-276-5509.


Licensing Contact:
Edward (Tedd) Fenn, J.D.
Email: tedd.fenn@nih.gov
Phone: 240-276-6833

OTT Reference No: E-088-2014/0
Updated: Aug 6, 2014