Immortalized Stria Vascularis Cell Line SV-k1


Available for nonexclusive licensing for research uses is the cell line, SV-k1, derived from the Organ of Corti. The line was developed from the stria vascularis, an organ localized on the lateral wall of the cochlea, adjacent to the Organ of Corti, containing cell populations specialized in the production of an endolymph very rich in K+ characteristic of the mammalian inner ear. SV-k1 cells express a set of biomarkers completely different of those expressed by OC-k3 cells, and are not sensitive to ototoxic drugs.

Potential Commercial Applications: Competitive Advantages:
  • Research
  • Hearing research
 


Inventors:

Gilda Canseco De Kalinec (NIDCD)  ➽ more inventions...

Frederico Kalinec (NIDCD)  ➽ more inventions...


Intellectual Property:
Research Material – Patent protection is not being pursued for this technology.

Publications:
Gratton MA, et al. PMID 11788196
Park C, et al. PMID 26854618
Espreafico EM, et al. PMID 9671730

Licensing Contact:
Michael Shmilovich, J.D.
Email: shmilovm@mail.nih.gov
Phone: 301-435-5019

OTT Reference No: E-013-2017-0
Updated: Nov 10, 2016