Immortalized Organ of Corti Cell Line OC-k3


Available for nonexclusive licensing as a research material is a conditionally immortalized Organ of Corti cell line called OC-k3. Sensory cells from the auditory organ, the Organ of Corti, are terminally differentiated and cannot be cultured. Moreover, few of them can be isolated per cochlea and survive only few hours after isolation making impossible to use on them many biochemical and molecular biology techniques. OC-k3, expresses many markers of sensory cells and it has already been used as an in vitro model for a variety of studies.

Potential Commercial Applications: Competitive Advantages:
  • Research
  • Hearing research
  • Susceptibility to ototoxic drugs
 


Inventors:

Gilda Canseco De Kalinec (NIDCD)  ➽ more inventions...

Frederico Kalinec (NIDCD)  ➽ more inventions...


Intellectual Property:
Research Material – Patent protection is not being pursued for this technology.

Publications:
Previati M, et al. PMID 17243113
Bertolaso L, et al. PMID 11781046

Licensing Contact:
Michael Shmilovich, J.D.
Email: shmilovm@mail.nih.gov
Phone: 301-435-5019

OTT Reference No: E-012-2017-0
Updated: Nov 10, 2016