User-friendly, Powerful Software for Analyzing ChIP-Seq Data

The present invention provides a user-friendly software, called PAPST (Peak Assignment and Profile Search Tool for ChIP-Seq), for bench scientists to work with ChIP-Seq data in seconds, allowing the scientists to screen genes against multiple genomic features with ease and efficiency previously not realized. Furthermore, PAPST may be used to identify genes of special significance in a wide variety of biological and biomedical fields, which could lead the discovery of disease-associated genes and the development of therapeutic methods for human diseases. Lastly, this powerful, easy-to-use software does not require any special computation expertise.

Potential Commercial Applications: Competitive Advantages:
  • Genomic analysis.
  • Drug target identification.
  • Easy to use.
  • Fast.
  • Either a stand-alone software or as an add-on to existing commercial software.

Development Stage:
  • Prototype
  • Pilot


Paul Bible (NIAMS)  ➽ more inventions...

Hong Sun (NIAMS)  ➽ more inventions...

Lai Wei (NEI)  ➽ more inventions...

Yuka Kanno (NIAMS)  ➽ more inventions...

Intellectual Property:
Research Tool – Patent protection is not being pursued for this technology.

Yang XP, et al. PMID 21278738
Yamane A, et al. PMID 21113164
Ghoreschi K, et al. PMID 20962846

Collaboration Opportunity:

The Biodata Mining & Discovery Section of the National Institute of Arthritis and Musculoskeletal and Skin Diseases is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize PAPST (Peak Assignment and Profile Search Tool for ChIP-Seq). For collaboration opportunities, please contact Hong-Wei Sun at 301-496-0016 or

Licensing Contact:
Admin. Licensing Specialist (ALS),

OTT Reference No: E-008-2012-0
Updated: Apr 23, 2013