Technology ID
E-305-2003-0

Recombinant Plasmids for Soluble Immunoreceptors

Linked ID
TAB-771
Inventors
Peter Sun (NIAID)
Lead Inventors
Peter Sun (NIAID)
Applications
Research Materials
ICs
NIAID
Commercial Applications
immunological research reagents development of diagnostic tools

Immunoreceptors initiate signals leading to the activation of immune system against invasion pathogens. A number of soluble receptors, representing the extracellular ligand binding domains of the immunoreceptors, have been expressed using a recombinant bacteria expression and reconstitution system. This set of 21 plasmids, which can be used as immunological research reagents or to develop diagnostic tools, comprise the following:

Plasmid Description
CD16-28b Soluble CD16
CD94 (S34) - 30a Soluble CD94 truncated at S34
CD94 (E51) - 30a Soluble CD94 truncated at E51
NKG2A (109R) - 30a Soluble NKG2A 109R construct
NKG2A (117G) - 30a Soluble NKG2A 117G construct
TBRII-30a Soluble type II TGF-beta receptor
C143-30a Soluble KIR2DL2 receptor
NKG2D-22b Soluble NKG2D receptor
ULBP-1-22-b Soluble ULBP-1
ULBP-2-22-b Soluble ULBP-2
ULBP-3-22b Soluble ULBP-3
HLA-E-30a Soluble HLA-E heavy chain
HLA-Cw3 Soluble HLA-Cw3 heavy chain
TREM-1-22b Soluble TREM-1 receptor
TREM-2-22b Soluble TREM-2 receptor
NKp30-22b Soluble NKp30
NKp46-22b Soluble NKp46
NKp44-22b Soluble NKp44
Siglec-3-30a Soluble Siglec-3
Siglec-5-30a Soluble Siglec-5
Siglec-7-30a Soluble Siglec-7

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