All Inventions from NIAID

  • Improved Live-Attenuated Vaccine for Respiratory Syncytial Virus (RSV) Bearing Codon-Pair Deoptimized NS1, NS2, N,...
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       Ref: E-104-2020-0 | Updated: Feb 25, 2021 | NIAID
  • Replication-Competent Adenovirus Type 4 SARS-CoV-2 Vaccines and Their Use
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       Ref: E-055-2021-0 | Updated: Feb 19, 2021 | NIAID
  • Antiviral Compounds with Broad Neutralization Capabilities
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       Ref: E-013-2006-1 | Updated: Feb 17, 2021 | NIAID
  • Epstein-Barr Virus Antibody That Blocks Fusion And Neutralizes Virus Infection of B Cells
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       Ref: E-020-2020-0 | Updated: Feb 16, 2021 | NIAID
  • Single-Chain Antibodies Directed to Norovirus GI.1 and GII.4 and Their Use
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       Ref: E-136-2013-0 | Updated: Feb 8, 2021 | NIAID
  • A VSV-EBOV-Based Vaccine Against COVID-19
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       Ref: E-258-2020-0 | Updated: Feb 5, 2021 | NIAID
  • Prefusion-Stabilized Fusion (F) Glycoprotein Vaccine Immunogens For Human Metapneumovirus
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       Ref: E-131-2019-0 | Updated: Jan 26, 2021 | NIAID
  • Hybridoma cell lines producing antibodies to RSV NS1
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       Ref: E-167-2018-0 | Updated: Jan 25, 2021 | NIAID
  • Stem Cell Factor-responsive FcepsilonRI Bearing Human Mast Cell Line LAD2
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       Ref: E-279-2001-0 | Updated: Jan 7, 2021 | NIAID
  • Antimalarial Inhibitors that Target the Plasmodial Surface Anion Channel (PSAC) Protein and Development of the PSAC...
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       Ref: E-145-2011-0 | Updated: Jan 5, 2021 | NIAID
  • Identification of a New Human Monoclonal Antibody that More Potently Prevents Malaria Infection
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       Ref: E-087-2019-0 | Updated: Nov 13, 2020 | NIAID
  • Recombinant Prefusion Measles and Mumps F and F–HN (H) Glycoproteins for Vaccine Development
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       Ref: E-153-2019-0 | Updated: Nov 5, 2020 | NIAID
  • Structure-Based Design of SARS-CoV-2 Spike Immunogens Stabilized in the RBD-All Down Conformation
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       Ref: E-187-2020-0 | Updated: Oct 5, 2020 | NIAID
  • Antibodies and Methods for the Diagnosis and Treatment of Epstein-Barr Virus Infection
    •    Ref: E-001-2017-0 | Updated: Sep 21, 2020 | NIAID
  • Methods for Dagnosing and Treating Mycobacterium tuberculosis (Mtb) Infection through Detection of CD153...
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       Ref: E-085-2018-0 | Updated: Sep 21, 2020 | NIAID
  • Use of the Intracellular Signaling Domain of Receptor CD28H as a Component of Chimeric Antigen Receptors to...
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       Ref: E-097-2020-0 | Updated: Sep 21, 2020 | NIAID
  • Self-Assembled Ferritin Nanoparticles Expressing Hemagglutinin as an Influenza Vaccine
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       Ref: E-293-2011-0 | Updated: Aug 3, 2020 | NIAID
  • A Varicella-Zoster Virus Mutant that is Markedly Impaired for Latent Infection Available for the Development of...
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       Ref: E-029-2007-0 | Updated: Jul 6, 2020 | NIAID
  • Broadly Protective Influenza Vaccine Comprising a Cocktail of Inactivated Avian Influenza Viruses
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       Ref: E-033-2018-0 | Updated: Jul 6, 2020 | NIAID
  • Cloned Genome of Infectious Hepatitis C Virus of Genotype 2a and Uses Thereof
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       Ref: E-100-1999-0 | Updated: Jul 6, 2020 | NIAID
  • Cloned Genomes Of Infectious Hepatitis C Virus And Uses Thereof
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       Ref: E-050-1998-0 | Updated: Jul 6, 2020 | NIAID
  • Diagnostic Reagents And Vaccines For Multiple Genotypes Of Hepatitis C Virus
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       Ref: E-120-1993-0 | Updated: Jul 6, 2020 | NIAID
  • Four Chimpanzee Monoclonal Antibodies that Neutralize Hepatitis A Virus
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       Ref: E-356-2001-0 | Updated: Jul 6, 2020 | NIAID
  • HCV/BVDV Chimeric Genomes and Uses Thereof
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       Ref: E-102-1999-0 | Updated: Jul 6, 2020 | NIAID
  • Infectious cDNA Clone of GB Virus B and Uses Thereof
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       Ref: E-173-1999-0 | Updated: Jul 6, 2020 | NIAID
  • Major Neutralization Site of Hepatitis E Virus and Use of this Neutralization Site in Methods of Vaccination
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       Ref: E-043-2000-0 | Updated: Jul 6, 2020 | NIAID
  • Monoclonal Antibodies Against Bacillus Anthracis Antigens
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       Ref: E-146-2004-0 | Updated: Jul 6, 2020 | NIAID
  • Monoclonal Antibodies Against Orthopoxviruses
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       Ref: E-145-2004-3 | Updated: Jul 6, 2020 | NIAID
  • Monoclonal Antibodies Specific for the E2 Glycoprotein of Hepatitis C Virus and Their Use in the Diagnosis,...
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       Ref: E-017-2001-0 | Updated: Jul 6, 2020 | NIAID
  • Monoclonal Antibodies That Bind or Neutralize Hepatitis B Virus
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       Ref: E-144-2004-0 | Updated: Jul 6, 2020 | NIAID
  • Monoclonal Antibodies that Neutralize Norovirus
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       Ref: E-226-2011-0 | Updated: Jul 6, 2020 | NIAID
  • Neutralizing Monoclonal Antibodies to Botulinum Neurotoxin Type A
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       Ref: E-180-2006-0 | Updated: Jul 6, 2020 | NIAID
  • North-2'-Deoxy-Methanocarbathymidines as Antiviral Agents Against Poxviruses
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       Ref: E-047-2005-0 | Updated: Jul 6, 2020 | NIAID
  • Polyvalent Influenza Virus-Like Particles (VLPs) and Use as Vaccines
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       Ref: E-195-2014-0 | Updated: Jul 6, 2020 | NIAID
  • Protein Nanoparticles for Antigen Display in Vaccines
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       Ref: E-005-2017-0 | Updated: Jul 6, 2020 | NIAID
  • Recombinant Proteins Of A Pakistani Strain Of Hepatitis E And Their Use In Diagnostic Methods And Vaccines
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       Ref: E-141-1992-2 | Updated: Jul 6, 2020 | NIAID
  • Recombinant Proteins of the Swine Hepatitis E Virus and Their Uses as a Vaccine and Diagnostic Reagents for Medical...
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       Ref: E-304-1998-0 | Updated: Jul 6, 2020 | NIAID
  • Swine Hepatitis E Virus Available For Use in Diagnosis, Prevention and Treatment of Hepatitis E
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       Ref: E-203-1997-0 | Updated: Jul 6, 2020 | NIAID
  • Two cDNA Clones of Hepatitis E Virus (HEV) that are Infectious for Primates and Encode a Virulent and an Attenuated...
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       Ref: E-278-2001-0 | Updated: Jul 6, 2020 | NIAID
  • Universal Influenza Virus Probes for Enrichment of Influenza Viral Sequences
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       Ref: E-032-2018-0 | Updated: Jul 6, 2020 | NIAID
  • Vaccine for Dengue Virus
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       Ref: E-171-1988-1 | Updated: Jul 6, 2020 | NIAID
  • Middle East Respiratory Syndrome Coronavirus Antibodies
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       Ref: E-239-2014-0 | Updated: Jun 24, 2020 | NIAID
  • A Rapid Ultrasensitive Assay for Detecting Prions Based on the Seeded Polymerization of Recombinant Normal Prion...
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       Ref: E-109-2007-0 | Updated: May 29, 2020 | NIAID
  • Alpha-Synuclein RT-QuIC: An Ultrasensitive Assay for the Detection of Alpha-Synuclein Seeding Activity Associated...
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       Ref: E-233-2017-0 | Updated: May 29, 2020 | NIAID
  • Prefusion Coronavirus Spike Proteins and Their Use
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       Ref: E-234-2016-0 | Updated: Apr 8, 2020 | NIAID
  • Continuous Cell Lines Persistently Expressing High Levels of Native HIV-1 Envelope Trimers on their Surface...
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       Ref: E-185-2018-0 | Updated: Mar 9, 2020 | NIAID
  • Ebola Virus Glycoprotein-Specific Monoclonal Antibodies and Uses Thereof
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       Ref: E-061-2018-0 | Updated: Mar 9, 2020 | NIAID
  • Improvement of Broadly HIV-Neutralizing Antibodies; Anti-HIV-1 Antibody VRC01.23 for Prevention or Treatment of HIV...
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       Ref: E-034-2018-0 | Updated: Mar 9, 2020 | NIAID
  • A High-Yield Perfusion-Based Transient Gene Expression Bioprocess
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       Ref: E-187-2018-0 | Updated: Dec 2, 2019 | NIAID
  • Methods to Increase Stability of Recombinant Vaccinia-Vectored Vaccines and Increase Expression of a Foreign Gene...
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       Ref: E-018-2010-0 | Updated: Oct 9, 2019 | NIAID
  • Recombinant HIV-1 Envelope Proteins and Their Use
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       Ref: E-240-2017-0 | Updated: Sep 5, 2019 | NIAID
  • Floxed Targeted Mouse Strain for Use in Conditional Deletion of the Irf8 Gene
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       Ref: E-062-2012-0 | Updated: Aug 27, 2019 | NIAID
  • Recombinant Nipah F Proteins and Their Use
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       Ref: E-050-2018-0 | Updated: Aug 21, 2019 | NIAID
  • HIV targets CD62L on central memory T cells through viral envelope glycans for adhesion and induces selectin...
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       Ref: E-261-2015-0 | Updated: Jul 31, 2019 | NIAID
  • Optimized Variants of the Broadly Neutralizing HIV-1 gp41 Antibody, 10E8
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       Ref: E-133-2015-0 | Updated: Nov 19, 2018 | NIAID
  • Fusion Glycoprotein Vaccine for Human Metapneumovirus
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       Ref: E-260-2014-0 | Updated: Oct 29, 2018 | NIAID
  • Recombinant Respiratory Syncytial Virus Challenge Strain
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       Ref: E-235-2018-0 | Updated: Oct 25, 2018 | NIAID
  • Use of Rostafuroxin to Inhibit Viral Infection
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       Ref: E-202-2018-0 | Updated: Oct 25, 2018 | NIAID
  • Recombinant HIV-1 Envelope Protein for Vaccine Use
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       Ref: E-178-2014-0 | Updated: Oct 18, 2018 | NIAID
  • HIV-1 Env Fusion Peptide Immunogens and Their Use
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       Ref: E-279-2016-0 | Updated: Oct 17, 2018 | NIAID
  • Self-assembling Insect Ferritin Nanoparticles for Display of Co-assembled Trimeric Antigens
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       Ref: E-270-2015-0 | Updated: Oct 17, 2018 | NIAID
  • Stabilized Group 2 Influenza Hemagglutinin Stem Region Trimers and Uses Thereof
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       Ref: E-228-2016-0 | Updated: Oct 17, 2018 | NIAID
  • Substitutions-Modified Prefusion RSV F Proteins and Their Use
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       Ref: E-064-2016-0 | Updated: Oct 17, 2018 | NIAID
  • Glycan-masked engineered outer domains of HIV-1 GP120 and Their Use
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       Ref: E-083-2017-0 | Updated: Oct 12, 2018 | NIAID
  • Attenuated Human Parainfluenza Virus Type 1 Expressing Ebola Virus Glycoprotein GP as an Intranasal Ebola Vaccine...
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       Ref: E-142-2018-0 | Updated: Oct 9, 2018 | NIAID
  • Recombinant RSV B1 expressing eGFP as a reporter gene
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       Ref: E-159-2018-0 | Updated: Oct 9, 2018 | NIAID
  • A New Class of Immunomodulatory Drugs for Multiple Sclerosis
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       Ref: E-064-2015-0 | Updated: Oct 2, 2018 | NIAID
  • Licensing Availability: Methods of Diagnosing and Treating CHAPLE, A Newly Identified Orphan Disease
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       Ref: E-251-2016-0 | Updated: Sep 7, 2018 | NIAID
  • Prefusion HPIV F Immunogens and Their Use.
    •    Ref: E-215-2016-0 | Updated: Aug 31, 2018 | NIAID
  • Inhibition of CD300f Function on Dendritic Cells Promotes Tumor Destruction
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       Ref: E-257-2016-0 | Updated: Jul 23, 2018 | NIAID
  • Recombinant Paramyxoviruses Expressing Optimized Heterologous Antigens
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       Ref: E-241-2014-0 | Updated: Jul 3, 2018 | NIAID
  • Broadly Neutralizing Antibodies Against HIV-1 Directed to the CD4 Binding Site of HIV Envelope Protein
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       Ref: E-300-2009-0 | Updated: Jun 22, 2018 | NIAID
  • Human-derived Monoclonal Antibody for Treatment of Ebola Virus Infection
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       Ref: E-045-2015-0 | Updated: Jun 22, 2018 | NIAID
  • Inhibition of Host Heme Oxygenase-1 as an Adjunctive Treatment to Improve the Outcome of Conventional Antibiotic...
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       Ref: E-174-2016-0 | Updated: Jun 22, 2018 | NIAID
  • Neutralizing Antibodies to Influenza HA and Their Use and Identification
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       Ref: E-061-2016-0 | Updated: Jun 22, 2018 | NIAID
  • Novel Multivalent Nanoparticle Vaccines
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       Ref: E-060-2015-0 | Updated: Jun 22, 2018 | NIAID
  • Recombinant Stabilized Prefusion Protein of Respiratory Syncytial Virus for Use as a Subunit Vaccine
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       Ref: E-081-2013-0 | Updated: Jun 22, 2018 | NIAID
  • Stabilized Influenza Hemagglutinin Stem Region Trimers and Uses Thereof
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       Ref: E-066-2014-0 | Updated: Jun 22, 2018 | NIAID
  • Zika Virus Vaccines
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       Ref: E-181-2016-0 | Updated: Jun 22, 2018 | NIAID
  • CD300b Expression Exacerbates Endotoxemia and Septic Peritonitis
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       Ref: E-112-2016-0 | Updated: Jun 11, 2018 | NIAID
  • Amino Acid Substitutions Mutants of Anthrax Protective Antigen, Lethal Factor, and Edema Factor
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       Ref: E-196-2014-0 | Updated: Jun 7, 2018 | NIAID
  • Antigens for Use in Loa Loa Microfilariae Quantitative Immunoassays
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       Ref: E-230-2014-0 | Updated: Jun 7, 2018 | NIAID
  • CCR9 Knockout Mice
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       Ref: E-200-2015-0 | Updated: Jun 7, 2018 | NIAID
  • CHO NL4-3 gp160
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       Ref: E-258-2015-0 | Updated: Jun 7, 2018 | NIAID
  • Edema Factor Adenylate Cyclase Variants Having Potencies That Are Highly Dependent On the N-end Rule
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       Ref: E-737-2013-0 | Updated: Jun 7, 2018 | NIAID
  • Expression, Purification, and Validation of Anthrax Toxin Proteins
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       Ref: E-201-2015-0 | Updated: Jun 7, 2018 | NIAID
  • HIV-1 Clone Bal.01
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       Ref: E-040-2014-0 | Updated: Jun 7, 2018 | NIAID
  • HIV-1 MW959 gp140 secreting CHO Cells
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       Ref: E-259-2015-0 | Updated: Jun 7, 2018 | NIAID
  • HIV-1 NL4-3 gp120 secreting CHO Cells
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       Ref: E-260-2015-0 | Updated: Jun 7, 2018 | NIAID
  • Non-invasive Method for Ebola Virus Infection Detection in Great Apes and Other Wildlife Hosts
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       Ref: E-006-2015-0 | Updated: Jun 7, 2018 | NIAID
  • pLAS-1 Plasmid
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       Ref: E-034-2017-0 | Updated: Jun 7, 2018 | NIAID
  • Pneumonia Virus of Mice Expression Vector PSynK-PVMJ3666
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       Ref: E-016-2015-0 | Updated: Jun 7, 2018 | NIAID
  • Polyclonal and Monoclonal Antibodies to Human Eosinophil Major Basic Protein, Eosinophil Peroxidase, Eosinophil...
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       Ref: E-286-2014-0 | Updated: Jun 7, 2018 | NIAID
  • Recombinant LL-SXP-1 and Plasmid Encoding LL-SXP-1 for the Immunodiagnosis of Loa Loa
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       Ref: E-003-2016-0 | Updated: Jun 7, 2018 | NIAID
  • Resurfaced Stabilized Core 3 (RSC3) Protein, Derived Proteins, and DNA Encoding These Proteins: RSC3, RSC3...
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       Ref: E-236-2016-0 | Updated: Jun 7, 2018 | NIAID
  • RL-5 – Rabbit T Cell Line Derived From a Herpesvirus Ateles-induced Rabbit Tumor From the Inbred Rabbit Line B/J...
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       Ref: E-104-2015-0 | Updated: Jun 7, 2018 | NIAID
  • WR (Western Reserve) Strain of Vaccinia Virus with K151E Mutation in A34R Gene
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       Ref: E-263-2015-0 | Updated: Jun 7, 2018 | NIAID
  • HIV Monoclonal Antibodies
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       Ref: E-109-2008-0 | Updated: May 18, 2018 | NIAID
  • A Prophylactic and Therapeutic for Preventing and Treating Tularemia by Rapid Activation of Host Cells and Antigen...
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       Ref: E-095-2008-0 | Updated: May 16, 2018 | NIAID
  • Anti-Vaccinia Monoclonal Antibody
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       Ref: E-123-2004-0 | Updated: May 16, 2018 | NIAID

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