Technologies related to Gene-based

Real-Time RT-PCR Detection of Rickettsia species -- PanR6/Total Nucleic Acid Assay with High Sensitivity and Specificity
Ref: E-230-2017/0 | Updated: Feb 27, 2018
Influenza A Virus Detection and Subtyping Directly from Animal Swabs and Environmental Samples
Ref: E-199-2016/0 | Updated: Feb 27, 2018
Monoclonal Antibodies for Specific Detection of Dengue Virus Sub-type 4 in Human Serum
Ref: E-057-2016/0 | Updated: Feb 12, 2018
DNA Probes to Rapidly Screen Candida glabrata Isolates for Echinocandin Resistance to Antifungal Treatment
Ref: E-132-2014/0 | Updated: Jan 9, 2018
West Nile/Zika Virus Chimeras for Inactivated Zika Vaccine and Diagnostic Assay Development
Ref: E-177-2016/0 | Updated: Dec 21, 2017
Rapid Colorimetric Detection of Zika Virus from Serum and Urine Specimens by RT-LAMP (Reverse Transcription Loop-Mediated Isothermal Amplification).
Ref: E-041-2017/0 | Updated: Feb 8, 2018
Chimeric Dengue/Zika Viruses for Live-Attenuated Zika Vaccine Development
Ref: E-178-2016/0 | Updated: Dec 4, 2017
Real-Time PCR Assay for Detection of Carbapenem Antibiotic Resistance Genes of the IMP-type
Ref: E-156-2017/0 | Updated: Dec 5, 2017
T Cell Receptors (TCRs) Targeting KRAS Mutants for Cancer Immunotherapy/Adoptive Cell Therapy
Ref: E-180-2015/0 | Updated: Dec 4, 2017
Real-Time RT-PCR Assay for the Rapid Detection of Rabies and Other Lyssaviruses
Ref: E-070-2016/0 | Updated: Nov 20, 2017
Functionally-Interdependent Shape-Switching Nucleic Acid Nanoparticles
Ref: E-277-2016/0 | Updated: Nov 17, 2017
A Rapid Method of Isolating Neoantigen-specific T Cell Receptor Sequences
Ref: E-067-2017/0 | Updated: Oct 10, 2017
Gene-based Diagnostic Predicts Patient Response to Cancer Immunotherapy
Ref: E-022-2017/0 | Updated: Nov 16, 2017
Efficient mRNA-Based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7
Ref: E-036-2015/0 | Updated: May 17, 2017
T-cells Transduced with HLA A11 restricted CT-RCC HERV-E reactive TCR to Treat Patients with ccRCC
Ref: E-120-2016/0 | Updated: May 17, 2017
Simple and Rapid Assay to Detect Acute Subtype B and Group M HIV-1 Infections
Ref: E-014-2015/0 | Updated: Mar 15, 2017
New T-cell Immunotherapy That Targets Aggressive Epithelial Tumors
Ref: E-153-2016/0 | Updated: Mar 3, 2017
Gene Signature Predictive of Hepatocellular Carcinoma Response to Transcatheter Arterial Chemoembolization (TACE)
Ref: E-101-2016/0 | Updated: Nov 17, 2016
Non-invasive Pan-Cancer Detection Method
Ref: E-177-2015/0 | Updated: Nov 8, 2016
Capsid-Free AAV Vectors for Gene Delivery and Their Use for Gene Therapy
Ref: E-241-2010/0 | Updated: Oct 12, 2016
Tagged Form of Mut Enzyme and Its Use in Gene Therapy
Ref: E-090-2015/0 | Updated: Apr 18, 2016
Gene Therapy for Niemann-Pick Disease Type C
Ref: E-185-2014/0 | Updated: Apr 18, 2016
Fetal Hemoglobin Induction for Treating Sickle Cell Disease and Thalassemias
Ref: E-038-2016/0 | Updated: Dec 10, 2015
TRPC Knockout (KO) Mice and Mice with a Floxed Allele of TRPC Ion Channel Genes
Ref: E-071-2014/2 | Updated: Dec 8, 2015
Mice with a Floxed Allele of the alpha Subunit of the Heterotrimeric G Protein Go or Gi2
Ref: E-071-2014/0 | Updated: Dec 8, 2015
SIRT1 KO Human Cell Lines Generated by CRISPR/Cas9-mediated DNA Editing
Ref: E-184-2015/0 | Updated: Nov 30, 2015
Mouse Model for Study of Diabetic Nephropathy and Role of Soluble Epoxide Hydrolase
Ref: E-292-2015/0 | Updated: May 24, 2016
Optimized Gene Therapy Vector for the Treatment of Glycogen Storage Disease Type Ia
Ref: E-039-2015/0 | Updated: Apr 26, 2017
mNFHcre Transgenic Mice
Ref: E-293-2009/0 | Updated: Aug 10, 2015
Modified AAV5 Vectors for Enhanced Transduction and Reduced Antibody Neutralization
Ref: E-097-2015/0 | Updated: Nov 1, 2017
A Novel Adeno-Associated Virus for Gene Therapy
Ref: E-175-2015/0 | Updated: Nov 1, 2017
WNT1-Induced Secreted Protein-1 Knockout Mouse Model
Ref: E-234-2015/0 | Updated: Aug 6, 2015
Real-time RT-PCR assay for Detection of Live Attenuated Influenza Vaccine for A and B Viruses
Ref: E-560-2013/0 | Updated: Sep 26, 2017
A Novel Therapeutic Vector for Hemoglobin Disorders
Ref: E-165-2014/0 | Updated: Sep 21, 2015
Transgenic Mouse Model of Human Open Angle Glaucoma
Ref: E-091-2015/0 | Updated: Jul 2, 2015
A Novel T Cell Therapy Against Patient-Specific Cancer Mutations
Ref: E-229-2014/0 | Updated: Mar 29, 2017
A Novel, Personalized T Cell Therapy: T-Cell Receptor Engineered T Cells Targeting Tumor Specific Mutations
Ref: E-233-2014/0 | Updated: Mar 29, 2017
Recombinant Paramyxoviruses Expressing Optimized Heterologous Antigens
Ref: E-241-2014/0 | Updated: Jun 27, 2017
Development of GPR124 Wildtype and Knockout Brain Endothelial Reporter Cells
Ref: E-079-2015/0 | Updated: Dec 12, 2017
IFN Gamma for Reducing Adverse Ocular Side Effects of MEK-Inhibitor Therapy in Cancer
Ref: E-248-2012/0 | Updated: Jul 1, 2015
Novel Cancer Immunotherapy: HLA-A11 Restricted T Cell Receptor That Recognizes G12D Variant of Mutated KRAS
Ref: E-028-2015/0 | Updated: Oct 13, 2015
Novel Immunotherapy for Cancer Treatment: Chimeric Antigen Receptors Targeting CD70 Antigen
Ref: E-021-2015/0 | Updated: Oct 13, 2015
CXCR4 Reduction Leads to Enhancement of Engraftment of Hematopoietic Stem Cells
Ref: E-173-2014/0 | Updated: Jul 1, 2015
GTF2I Mutations as Genetic Marker for Prognosis of Thymic Malignancies
Ref: E-109-2014/0 | Updated: Jul 1, 2015
Systems and Devices for Training and Imaging an Awake Test Animal
Ref: E-043-2015/0 | Updated: May 2, 2017
T Cell-Based Adoptive Transfer Immunotherapy for Polyomavirus-Associated Pathologies
Ref: E-166-2014/0 | Updated: Sep 12, 2017
LRRK2 Inhibitors: Novel Treatment for Intestinal Bowel Disorders
Ref: E-070-2014/0 | Updated: Mar 22, 2016
A Novel Virus-Based Expression System
Ref: E-181-2014/0 | Updated: Aug 18, 2015
T-cell Chimeric Receptors of TSLPR for Diagnosis and Immunotherapy of Cancer
Ref: E-008-2014/0 | Updated: Nov 20, 2014
High-Titer, Fast-Growth Chimeric Dengue/West Nile Viruses for Vaccine and Diagnostics Development
Ref: E-168-2014/0 | Updated: Nov 14, 2014
The Use of Chimeric Antigen Receptor to Control HIV Infection
Ref: E-212-2014/0 | Updated: Sep 9, 2015
Chimeric Receptors Targeting CD-19
Ref: E-042-2014/0 | Updated: Oct 28, 2014
A Novel Fusion Protein for Inhibiting HIV Budding
Ref: E-223-2014/0 | Updated: Sep 9, 2015
Cancer Immunotherapy Using Virus-like Particle Containing Alphavirus Replicons Coding for Therapeutic Proteins
Ref: E-050-2014/0 | Updated: Jun 27, 2016
Novel Anti-HIV Compounds (Peptides or Peptide Mimetics)
Ref: E-019-2014/0 | Updated: Sep 10, 2014
AAV-Vectors for Treatment of Glycogen Storage Disorders
Ref: E-552-2013/0 | Updated: Aug 6, 2014
Lentiviral Vectors to Modulate p53 Function in Human Stem Cells
Ref: E-137-2010/0 | Updated: Aug 6, 2014
Nucleic Acid Nanoparticles for Triggering RNA Interference
Ref: E-156-2014/0 | Updated: Sep 9, 2015
Multifunctional RNA Nanoparticles as Therapeutic Agents
Ref: E-765-2013/0 | Updated: Nov 14, 2016
Novel Anti-HIV Proteins from Coral Reefs
Ref: E-295-2012/0 | Updated: May 20, 2015
RNA Splicing Inhibitors to Treat Cancers
Ref: E-065-2014/0 | Updated: Jun 9, 2014
On-site in vitro Diagnostic: Real-time Loop-Mediated Isothermal Amplification Detection of HIV-2 Groups A and B
Ref: E-020-2014/0 | Updated: Jun 2, 2014
Multiplex Assay for Rapid Salmonella Serotyping from Human, Animal, Food and Environmental Sources
Ref: E-149-2013/0 | Updated: Jun 27, 2016
MDCK-based Reporter System for Detection of Influenza Viruses, Antiviral Drug Screening, and Analysis of Neutralizing Antibodies
Ref: E-185-2013/0 | Updated: May 15, 2014
Discrete Cross-Reactive Epitopes for Flavivirus Serological Diagnostics and Vaccines
Ref: E-333-2013/0 | Updated: May 15, 2014
A Device for Simultaneous and Rapid Diagnosis and Detection of Recent and Long Term HIV-1 Infection
Ref: E-357-2013/0 | Updated: May 15, 2014
Multi-specific Chimeric Antigen Receptors Against HIV
Ref: E-170-2013/0 | Updated: Oct 23, 2017
Compositions for Modification of Genomic DNA and Exogenous Gene Expression
Ref: E-763-2013/0 | Updated: Apr 14, 2014
Engineering Neural Stem Cells Using Homologous Recombination
Ref: E-762-2013/0 | Updated: Apr 14, 2014
Treating or Inhibiting JC Polyomavirus Infection and JC Polyomavirus-Associated Progressive Multifocal Leukoencephalopathy
Ref: E-549-2013/0 | Updated: Apr 15, 2014
Dengue Vaccines: Tools for Redirecting the Immune Response for Safe, Efficacious Dengue Vaccination
Ref: E-289-2013/0 | Updated: Mar 18, 2014
Human Influenza Virus Real-time RT-PCR: Detection and Discrimination of Influenza A (H3N2) Variant from Seasonal Influenza A (H3N2) Viruses, Including H3v and Seasonal H3 Assays
Ref: E-562-2013/0 | Updated: Mar 18, 2014
Rabies Vaccine for the Oral Immunization of Domesticated Animals, Wildlife and Feral Animals
Ref: E-470-2013/0 | Updated: May 24, 2016
Use of Soluble CD27 as Potential Immunotherapy and a Diagnostic and Prognostic Serum Biomarker for Solid Tumors
Ref: E-005-2011/0 | Updated: Oct 23, 2017
Multivalent, Multiple-Antigenic-Peptides for Serological Detection of HIV-1 Groups -M, -N, -O, and HIV-2
Ref: E-604-2013/0 | Updated: Feb 28, 2014
Peptide Sequences for Chlamydophila pneumoniae Vaccine and Serological Diagnosis
Ref: E-235-2013/0 | Updated: Feb 7, 2014
Multiple Antigenic Peptide Assays for Detection of HIV and SIV Type Retroviruses
Ref: E-294-2013/0 | Updated: Feb 7, 2014
Recombinant Polypeptides for Clinical Detection of Taenia solium and Diagnosis of Cysticercosis
Ref: E-230-2013/0 | Updated: Feb 6, 2014
Enterovirus Molecular Diagnostic Test Kit
Ref: E-257-2013/0 | Updated: Feb 6, 2014
Methods of Retaining Methylation Pattern Information in Globally Amplified DNA
Ref: E-243-2013/0 | Updated: Feb 6, 2014
Multivalent Immunogenic Peptides (Vaccines) for the Treatment of Prostate and Breast Cancer
Ref: E-047-2014/0 | Updated: Oct 23, 2017
Improved Personalized Cancer Immunotherapy: Rapid Selection of Tumor Reactive T Cells Based on Expression of Specific Cell Surface Markers from Peripheral Blood
Ref: E-085-2013/0 | Updated: Oct 13, 2015
Novel One-Well Limiting-Antigen Avidity Enzyme Immunoassay to Detect Recent HIV-1 Infection Using a Multi-subtype Recombinant Protein
Ref: E-522-2013/0 | Updated: Jan 29, 2014
Molecular Detection and Viral-Load Quantification for HIV-1 Groups M, N and O, and Simian Immunodeficiency Virus-cpz (SIVcpz)
Ref: E-271-2013/0 | Updated: Jan 28, 2014
Virus Replicon Particles as Rift Valley Fever Vaccines
Ref: E-272-2013/0 | Updated: Aug 8, 2016
Photoinduced Electron Transfer Fluorescent Primer for Nucleic Acid Amplification
Ref: E-292-2013/0 | Updated: Feb 17, 2016
Vaccine Attenuation via Deoptimization of Synonymous Codons
Ref: E-328-2013/0 | Updated: Jan 28, 2014
Recombinant Nucleic-Acid Based Flavivirus Nucleic Acids for Development of Vaccines and/or Sero-diagnostics
Ref: E-341-2013/0 | Updated: Jan 28, 2014
Stable, Early-stage Biomarker for Diagnosis of Bacillus anthracis Infection and Anthrax Vaccine Development
Ref: E-474-2013/0 | Updated: Mar 3, 2017
Simple, Rapid, and Sensitive Real-Time PCR Assays for Detecting Drug Resistance of HIV
Ref: E-198-2013/0 | Updated: Mar 12, 2018
Fluorescent Primer(s) Creation for Nucleic Acid Detection and Amplification
Ref: E-252-2013/0 | Updated: Jan 27, 2014
Select M. tuberculosis Peptides as Mucosal Vaccines Against Pulmonary Tuberculosis
Ref: E-192-2013/0 | Updated: Jan 27, 2014
Real-time PCR Assays for Human Bocavirus Detection and Diagnosis
Ref: E-213-2013/0 | Updated: Jan 27, 2014
Detection of Retroviruses and HIV-1 Groups -M and -O Discrimination within Clinical Serum Samples
Ref: E-232-1993/0 | Updated: Jan 27, 2014
Antigen, Encoding Gene, Related Monoclonal Antibody and Hybridoma Clones for Streptococcus pneumoniae Serological Diagnostics
Ref: E-157-1991/0 | Updated: Jan 20, 2014
Immunogenic Hepatitis E Virus Polypeptides for Vaccine and Diagnostics Development
Ref: E-152-2013/0 | Updated: Jan 20, 2014
Rapid Detection of Antiretroviral(s) Drug-Resistant HIV-1 within Clinical Samples
Ref: E-129-2013/0 | Updated: Jan 20, 2014
Real-time RT-PCR Assay for the Detection of Rift Valley Fever Virus in Humans and Livestock
Ref: E-187-2013/0 | Updated: Jan 16, 2014
Universal Diagnostic Assay for Detection and Identification of Poxviruses in Clinical Samples
Ref: E-265-2013/0 | Updated: Jan 16, 2014
Real-time PCR and High Resolution Melt Analysis for Genotyping of Chlamydophila psittaci
Ref: E-266-2013/0 | Updated: Jan 23, 2014


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