Methods and Apparatus for Computer-Aided Cough Sound Analysis


CDC researchers have developed a system that allows subjects to cough into a tubing system allowing the acoustics generated to be recorded with high fidelity and generated data is transferred to a computer for subsequent analysis. Lung diseases can be differentiated by the location of effect in the lungs that produce variations in cough sounds and patterns. Based on these differences, analysis software estimates the lung disease type of the subject. Those who benefit from cough sound analysis include subjects in the early stages of undetected lung disease, subjects with conditions not easily diagnosed by standard techniques, subjects who demonstrate difficulty performing forced expiratory maneuvers and other pulmonary function tests (e.g., elderly, young and very sick patients), and workers whose respiratory functioning may change during the workday.

Potential Commercial Applications: Competitive Advantages:
  • Clinical screening for early-stage respiratory illnesses
  • Occupational health and safety
  • Physiological data collection and algorithmic analysis
  • Preventative and early intervention health care
 
  • Increased accuracy in recorded observations
  • Improved objectivity in analysis compared to traditional auscultatory methods
  • Broadens the diagnostic toolset of primary/initial care physicians and respiratory therapists
  • Portable for field studies and on-site screening/ diagnostic uses


Development Stage:
  • In situ data available (on-site)
  • Prototype


Related Invention(s):
E-283-2013/0


Inventors:

William Goldsmith (CDC)  ➽ more inventions...

David Frazer (CDC)  ➽ more inventions...

Jeffrey Reynolds (CDC)  ➽ more inventions...

Aliakbar Afshari (CDC)  ➽ more inventions...

Kimberly Friend (CDC)  ➽ more inventions...

Walter McKinney (CDC)  ➽ more inventions...


Intellectual Property:
U.S. Pat: 2,269,992 issued 2009-12-22
U.S. Pat: 6,436,057 issued 2002-08-20
US Application No. 60/130,864

Publications:
Wysong P. Ever Wonder What a Cough Looks Like? The Medical Post 1998;34(21):14. PMID 19930559
Abaza AA, et al. PMID 19876736
Goldsmith WT, et al.

Licensing Contact:
Karen Surabian, J.D., M.B.A.
Email: karen.surabian@nih.gov
Phone: 301-594-9719

OTT Reference No: E-245-2013/0
Updated: Jul 22, 2014