FY-2015 Top 20 Commercially Successful Inventions
(based on royalties on product sales)
 |
VACCINES & THERAPEUTICS | ||
| Rank | |||
| 1 | Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 | Erickson et al. | NCI |
| 2 | HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins | Lowy et al. | NCI |
| 5 | Proteosome Inhibitor for Treatment of Multiple Myeloma | Gupta et al. | NCI |
| 7 | Nutritional Supplement to Treat Macular Degeneration | Ferris et al. | NEI |
| 8 | Vaccinia Virus Vector Used in Biologicals/Vaccines | Moss et al. | NIAID |
| 9 | Palifermin for Treatment of Oral Mucositis | Rubin et al. | NCI |
| 17 | Use of the Progesterone Receptor Modulator CDB-2914 for Treating Uterine Fibroids | Nieman et al. | NICHD |
 |
DIAGNOSTICS | ||
| Rank | |||
| 4 | Cloned DNA Sequences, Hybridizable with Genomic RNA of Lymphadenopathy-Associated Virus (LAV) | Alizon et al. | EM |
| 6 | DNA Probe for Breast Cancer Diagnosis (HER-2) | King et al. | NCI |
| 12 | Synthetic HIV Protease Gene and Method for Its Expression | Medabalimi et al. | NCI |
| 16 | Diagnostic for Norwalk-like Virus | Green et al. | NIAID |
 |
INSTRUMENTATION & DEVICES | ||
| Rank | |||
| 10 | Diffusion Tensor Magnetic Resonance Imaging | Basser et al. | NICHD |
| 13 | Paclitaxel-Eluting Peripheral Stent System | Kinsella et al. | NIA |
| 15 | Films Containing Energy-Absorbing Dyes for Microdissection | Bonner et al. | NIBIB |
 |
RESEARCH MATERIALS | ||
| Rank | |||
| 3 | Monoclonal Antibody for Treatment of RSV | Murphy et al. | NIAID |
| 11 | Digital PCR | Silver et al. | NIAID |
| 14 | Purified Transforming Growth Factor Beta (TGF-beta) | Sporn et al. | NCI |
| 18 | Cell line H12F3 | Shevach | NIAID |
| 19 | Stem Cell Factor-Responsive FϲεRI Bearing Human Mast Cell Line LAD2 | Kirshenbaum et al. | NIAID |
| 20 | Cloned, Hormone-Producing Choriocarcinoma Cell Lines | Kohler | NICHD |