FY-2009 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoules VACCINES & THERAPEUTICS
Rank      
1 HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins Lowy et al. NCI
2 Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 Erickson et al. NCI
3 Monoclonal Antibody for Treatment of RSV Murphy et al. NIAID
4 Synthetic Thyrotropin as Adjuvant in Thyroid Cancer Wondisford et al. NIDDK
5 Proteosome Inhibitor for Treatment of Multiple Myeloma Gupta et al. NCI
7 AIDS Drug ddI Mitsuya et al. NCI
8 Nutritional Supplement to Treat Macular Degeneration Ferris et al. NEI
11 Paclitaxel as a Cancer Treatment Wilson et al. NCI
13 Vaccinia Virus Vector Used in Veterinary Biologicals/Vaccines Moss et al. NIAID
17 Radioimmunotherapy for Non-Hodgkin's Lymphoma Gansow et al. NCI
 
 
photo: human puzzle with stethoscope DIAGNOSTICS
Rank      
9 Serological Detection of Antibodies to HIV-1 Gallo et al. NCI
10 DNA Probe for Breast Cancer Diagnosis King et al. NCI
14 Genoyping of HIV Protease Gene Oroszlan et al. NCI
18 Norwalk Virus - IVD Product Green et al. NIAID
 
 
abstract illustration: instrumentation INSTRUMENTATION & DEVICES
Rank      
6 Paclitaxel-Eluting Coronary Stent System Kinsella et al. NIA
12 Diffusion Tensor Magnetic Resonance Imaging Basser et al. NICHD
15 Laser Capture Microdissection Liotta et al. NCI
16 Enhanced Magnetic Resonance Imaging Through Magnetization Transfer Balaban et al. NHLBI
 
 
photo: laboratory glassware RESEARCH MATERIALS
Rank      
19 Purified Transforming Growth Factor Beta (TGF-beta) Sporn et al. NCI
20 Neutrophil Chemotactic Factor (IL-8) Matsushima et al. NCI