Technologies related to Early-stage

Novel Human Rotavirus Vaccine CDC-6 Strain for Impacted Subgroup, the Lewis Negative Population
Ref: E-285-2015/0 | Updated: Mar 9, 2018
Near Real-time, Low-cost, Hand-held Sensors for Measuring Elemental Concentration of Airborne Particles for Indoor or Outdoor Air Quality Monitoring
Ref: E-291-2016/0 | Updated: Feb 27, 2018
Heartland Virus Humanized Monoclonal Antibodies for Diagnostic and Therapeutic Development
Ref: E-293-2014/1 | Updated: Feb 14, 2018
Regenerative Therapy for Cartilage Damage
Ref: E-152-2017/0 | Updated: Jan 25, 2018
T Cell Receptors (TCRs) Targeting KRAS Mutants for Cancer Immunotherapy/Adoptive Cell Therapy
Ref: E-180-2015/0 | Updated: Dec 4, 2017
Chimeric Dengue/Zika Viruses for Live-Attenuated Zika Vaccine Development
Ref: E-178-2016/0 | Updated: Dec 4, 2017
Hypoxia Inducible Factor 1 (HIF-1) Inhibitors
Ref: E-115-2015/0 | Updated: Nov 20, 2017
Progressive and Multipath Holistically Nested Neural Network for Improved Detail Level in Medical Image Segmentation
Ref: E-109-2017/0 | Updated: Nov 17, 2017
Hybrid Computer Tomography Scanning System
Ref: E-175-2017/0 | Updated: Aug 23, 2017
Convolutional Neural Networks for Organ Segmentation
Ref: E-182-2016/0 | Updated: Jun 23, 2017
Computer-Aided Diagnostic for Use in Multiparametric MRI for Prostate Cancer
Ref: E-183-2016/0 | Updated: Jun 23, 2017
Method and System of Building Hospital-Scale Medical Image Database
Ref: E-076-2017/0 | Updated: Jun 23, 2017
Efficient mRNA-Based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7
Ref: E-036-2015/0 | Updated: May 17, 2017
T-cells Transduced with HLA A11 restricted CT-RCC HERV-E reactive TCR to Treat Patients with ccRCC
Ref: E-120-2016/0 | Updated: May 17, 2017
cGAP-PNA Multivalent Ligand Display at the Nanoscale
Ref: E-761-2013/0 | Updated: Apr 18, 2017
Simple and Rapid Assay to Detect Acute Subtype B and Group M HIV-1 Infections
Ref: E-014-2015/0 | Updated: Mar 15, 2017
New T-cell Immunotherapy That Targets Aggressive Epithelial Tumors
Ref: E-153-2016/0 | Updated: Mar 3, 2017
A New Class of Stable Heptamethine Cyanine Fluorophores and Biomedical Applications Thereof
Ref: E-271-2014/0 | Updated: Nov 22, 2017
Anti-CD133 Monoclonal Antibodies as Cancer Therapeutics
Ref: E-025-2015/0 | Updated: Feb 13, 2017
Methods for Improving Drug Delivery to the Central Nervous System
Ref: E-179-2016/0 | Updated: Feb 13, 2017
Polyvalent Influenza Virus-Like Particles (VLPs) and Use as Vaccines
Ref: E-195-2014/0 | Updated: Dec 1, 2016
Non-invasive Pan-Cancer Detection Method
Ref: E-177-2015/0 | Updated: Nov 8, 2016
Capsid-Free AAV Vectors for Gene Delivery and Their Use for Gene Therapy
Ref: E-241-2010/0 | Updated: Oct 12, 2016
Enhanced Functionalization of Carbon Nanoparticles for Biomedical Applications
Ref: E-207-2016/0 | Updated: Oct 13, 2016
Albumin Binding Immunomodulatory Compositions
Ref: E-149-2016/0 | Updated: Jun 22, 2016
Alloreactive T Cell Depletion Method For Preventing Graft-Versus-Host Disease
Ref: E-125-2015/0 | Updated: Jun 22, 2016
Chimeric Antigen Receptors to CD276 for Treating Cancer
Ref: E-243-2015/0 | Updated: May 25, 2016
Thalidomide Analogs that Inhibit Inflammation and Angiogenesis
Ref: E-208-2015/0 | Updated: Jan 4, 2016
Mice with a Floxed Allele of the alpha Subunit of the Heterotrimeric G Protein Go or Gi2
Ref: E-071-2014/0 | Updated: Dec 8, 2015
TRPC Knockout (KO) Mice and Mice with a Floxed Allele of TRPC Ion Channel Genes
Ref: E-071-2014/2 | Updated: Dec 8, 2015
Assays for Measuring and Quantifying DNA Damage from Ionizing Radiation, Chemotherapeutic Agents, and Environmental Agents
Ref: E-276-2014/0 | Updated: Dec 1, 2015
SIRT1 KO Human Cell Lines Generated by CRISPR/Cas9-mediated DNA Editing
Ref: E-184-2015/0 | Updated: Nov 30, 2015
A Novel Rapid Point-of Care Diagnostic Method for Infectious and Autoimmune Diseases
Ref: E-190-2015/0 | Updated: Sep 23, 2015
Three-Dimensional Curved Catheter for Right Atrial Appendage Traversal
Ref: E-078-2015/0 | Updated: Sep 9, 2015
Genome Wide DNase I Hypersensitive Sites Detection in Formalin-Fixed Paraffin-Embedded Single Cells
Ref: E-254-2014/0 | Updated: Aug 17, 2015
Anti-CD47 Antibodies for the Treatment of Cancer
Ref: E-263-2014/0 | Updated: Sep 10, 2015
Rabbit Antisera to Various Matrix, Matricellular, and Other Secreted Proteins
Ref: E-135-2008/0 | Updated: Aug 11, 2015
Novel Treatment for Anemia and Polycythemia: AVPR1B Molecules Modulating Erythropoiesis
Ref: E-619-2013/0 | Updated: Aug 6, 2015
Modified AAV5 Vectors for Enhanced Transduction and Reduced Antibody Neutralization
Ref: E-097-2015/0 | Updated: Nov 1, 2017
Magnetic Resonance Magnification Imaging
Ref: E-252-2014/0 | Updated: Jan 12, 2017
Boron Amino Acid Mimetics for PET Imaging of Cancer
Ref: E-135-2015/0 | Updated: Jun 29, 2015
Swing-Away Winch Cathhead Guard
Ref: E-568-2013/0 | Updated: Jun 25, 2015
Emergency Maritime Battery Charger
Ref: E-567-2013/0 | Updated: Jun 25, 2015
A Novel Therapeutic Vector for Hemoglobin Disorders
Ref: E-165-2014/0 | Updated: Sep 21, 2015
A Novel T Cell Therapy Against Patient-Specific Cancer Mutations
Ref: E-229-2014/0 | Updated: Mar 29, 2017
Recombinant Paramyxoviruses Expressing Optimized Heterologous Antigens
Ref: E-241-2014/0 | Updated: Jun 27, 2017
Novel Immunotherapy for Cancer Treatment: Chimeric Antigen Receptors Targeting CD70 Antigen
Ref: E-021-2015/0 | Updated: Oct 13, 2015
IFN Gamma for Reducing Adverse Ocular Side Effects of MEK-Inhibitor Therapy in Cancer
Ref: E-248-2012/0 | Updated: Jul 1, 2015
Novel Cancer Immunotherapy: HLA-A11 Restricted T Cell Receptor That Recognizes G12D Variant of Mutated KRAS
Ref: E-028-2015/0 | Updated: Oct 13, 2015
CXCR4 Reduction Leads to Enhancement of Engraftment of Hematopoietic Stem Cells
Ref: E-173-2014/0 | Updated: Jul 1, 2015
Systems and Devices for Training and Imaging an Awake Test Animal
Ref: E-043-2015/0 | Updated: May 2, 2017
GTF2I Mutations as Genetic Marker for Prognosis of Thymic Malignancies
Ref: E-109-2014/0 | Updated: Jul 1, 2015
T Cell-Based Adoptive Transfer Immunotherapy for Polyomavirus-Associated Pathologies
Ref: E-166-2014/0 | Updated: Sep 12, 2017
LRRK2 Inhibitors: Novel Treatment for Intestinal Bowel Disorders
Ref: E-070-2014/0 | Updated: Mar 22, 2016
Aza-Englerin Analogues - Novel Natural Product-Based Nitrogen-Containing Anti-Cancer Agents
Ref: E-090-2014/0 | Updated: Jan 13, 2015
Highly Sensitive Tethered-Bead Immune Sandwich Assay
Ref: E-188-2014/0 | Updated: Jan 13, 2015
Cannabinoid Receptor Meditating Compounds for Metabolic Disease
Ref: E-140-2014/0 | Updated: Aug 23, 2017
Ultra-sensitive Diagnostic Detects fg/mL-pg/mL Pathogen/Disease Protein by Visual Color Change
Ref: E-167-2014/0 | Updated: Sep 17, 2015
A Novel Virus-Based Expression System
Ref: E-181-2014/0 | Updated: Aug 18, 2015
Microscopy System for Distinguishing Stimulated Emissions as a Means of Increasing Signal
Ref: E-247-2014/0 | Updated: Dec 11, 2014
Photo-Controlled Removal of Targets In Vitro and In Vivo
Ref: E-209-2014/0 | Updated: Oct 9, 2014
Device and System for Enhancing Cardiopulmonary Resuscitation
Ref: E-224-2014/0 | Updated: Oct 9, 2014
Chimeric Receptors Targeting CD-19
Ref: E-042-2014/0 | Updated: Oct 28, 2014
Novel Epstein-Barr Virus Vaccines
Ref: E-531-2013/0 | Updated: Dec 17, 2015
Novel Anti-HIV Compounds (Peptides or Peptide Mimetics)
Ref: E-019-2014/0 | Updated: Sep 10, 2014
Implantable Medical Devices with Electric Current Retrieval Assist
Ref: E-088-2014/0 | Updated: Aug 6, 2014
Interactive Protocol Services
Ref: E-172-2014/0 | Updated: Mar 31, 2017
Therapeutic for Glioblastoma Multiforme and Other Cancers
Ref: E-187-2012/0 | Updated: Feb 13, 2018
Novel Anti-HIV Proteins from Coral Reefs
Ref: E-295-2012/0 | Updated: May 20, 2015
Treatment of Chronic Kidney Disease with Synthetic Amphipathic Peptides
Ref: E-743-2013/0 | Updated: Jun 2, 2014
RNA Splicing Inhibitors to Treat Cancers
Ref: E-065-2014/0 | Updated: Jun 9, 2014
Occupational Safety: Portable Exposure Assessment System for Prevention of Musculoskeletal Injury
Ref: E-168-2013/0 | Updated: May 27, 2014
A Device for Simultaneous and Rapid Diagnosis and Detection of Recent and Long Term HIV-1 Infection
Ref: E-357-2013/0 | Updated: May 15, 2014
Compositions for Modification of Genomic DNA and Exogenous Gene Expression
Ref: E-763-2013/0 | Updated: Apr 14, 2014
Engineering Neural Stem Cells Using Homologous Recombination
Ref: E-762-2013/0 | Updated: Apr 14, 2014
Role of Novel Hepatitis Delta Virus Variant in Sjogren’s Syndrome
Ref: E-736-2013/0 | Updated: Apr 14, 2014
Treating or Inhibiting JC Polyomavirus Infection and JC Polyomavirus-Associated Progressive Multifocal Leukoencephalopathy
Ref: E-549-2013/0 | Updated: Apr 15, 2014
SCGB3A2 for Treatment of Cancer
Ref: E-286-2006/3 | Updated: Apr 15, 2014
Novel Small Molecule Antimalarials for Elimination of Malaria Transmission
Ref: E-751-2013/0 | Updated: Nov 18, 2015
Human Antibodies Against Middle East Respiratory Syndrome Coronavirus
Ref: E-002-2014/0 | Updated: Nov 28, 2017
Monoclonal Antibody Fragments for Targeting Therapeutics to Growth Plate Cartilage
Ref: E-003-2014/0 | Updated: Jun 29, 2017
Human iPSC-Derived Mesodermal Precursor Cells and Differentiated Cells
Ref: E-342-2013/0 | Updated: Mar 18, 2014
Deconvolution Software for Modern Fluorescence Microscopy
Ref: E-038-2014/0 | Updated: Mar 18, 2014
Mining Safety: Personal Dust Monitor Filters for Accurate, Quantifiable Spectrometric Analysis and Assessment of Worker Exposure Levels
Ref: E-312-2013/0 | Updated: Mar 11, 2014
Use of Soluble CD27 as Potential Immunotherapy and a Diagnostic and Prognostic Serum Biomarker for Solid Tumors
Ref: E-005-2011/0 | Updated: Oct 23, 2017
Recombinant Sulfated HIV Envelope Protein and Methods for Making Protein
Ref: E-067-2012/0 | Updated: Apr 15, 2014
Device to Measure Muscle Contractile-Relaxant and Epithelial Bioelectric Responses of Perfused, Intact Tracheal Airways Tissue In Vitro
Ref: E-246-2013/0 | Updated: Jan 27, 2014
Novel Primate T-cell Lymphotropic Viruses (HTLV, STLV) for Development of Diagnostics, Therapeutics, Research Tools, and Vaccines
Ref: E-281-2013/0 | Updated: May 24, 2016
Methods of Treating or Preventing Pruritis (Itch)
Ref: E-485-2013/0 | Updated: Jan 16, 2014
Improved Therapeutic Immunotoxins
Ref: E-771-2013/0 | Updated: Sep 6, 2017
Detection and Differentiation of Pathogenic Fungi in Clinical Samples Using a Multi-Analyte Profiling System
Ref: E-293-2013/0 | Updated: Jan 23, 2014
Diisocyanate Specific Monoclonal Antibodies for Occupational and Environmental Monitoring of Polyurethane Production Exposure-related Asthma and Allergy and Clinical Diagnosis
Ref: E-189-2013/0 | Updated: Jan 23, 2014
Chimeric Antigen Receptors to CD276 (B7-H3) for Treatment of Cancer
Ref: E-104-2013/0 | Updated: Nov 28, 2017
Improved Protein Quantification Process and Vaccine Quality Control Production
Ref: E-212-2013/0 | Updated: Dec 23, 2013
Novel Epitopes of Bacillus anthracis Lethal Factor for Development of Diagnostics and Therapeutics
Ref: E-210-2013/0 | Updated: Mar 3, 2017
Chimeric Antigen Receptors to ALK for Treating Neuroblastoma and Other Solid Tumors
Ref: E-007-2014/0 | Updated: Jan 18, 2018
Non-invasive Early Stage Lung Cancer Diagnostic and Prognostic Assays
Ref: E-121-2013/0 | Updated: Jul 1, 2015
Mouse Model for Methylmalonic Acidemia, an Inherited Metabolic Disorder
Ref: E-285-2011/1 | Updated: Dec 3, 2013
Methods of Modulating Chemotherapeutic Cytotoxicity
Ref: E-296-2011/0 | Updated: Sep 21, 2015
Diagnostics, Vaccines, and Delivery-Vehicles Related to Novel Phlebovirus
Ref: E-269-2013/0 | Updated: Dec 4, 2013


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