Technologies related to Therapeutic (biologic)

Heartland Virus Humanized Monoclonal Antibodies for Diagnostic and Therapeutic Development
Ref: E-293-2014/1 | Updated: Feb 14, 2018
Regenerative Therapy for Cartilage Damage
Ref: E-152-2017/0 | Updated: Jan 25, 2018
T Cell Receptors (TCRs) Targeting KRAS Mutants for Cancer Immunotherapy/Adoptive Cell Therapy
Ref: E-180-2015/0 | Updated: Dec 4, 2017
Antibody Targeting PD1 for Cancer Immunotherapy
Ref: E-167-2016/0 | Updated: Nov 29, 2017
Functionally-Interdependent Shape-Switching Nucleic Acid Nanoparticles
Ref: E-277-2016/0 | Updated: Nov 17, 2017
Neutralizing Antibodies to Influenza HA and Their Use and Identification
Ref: E-061-2016/0 | Updated: Oct 31, 2017
A Rapid Method of Isolating Neoantigen-specific T Cell Receptor Sequences
Ref: E-067-2017/0 | Updated: Oct 10, 2017
Chimeric Antibodies Against Hepatitis B e-Antigen
Ref: E-192-2017/0 | Updated: Jan 31, 2018
Efficient mRNA-Based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7
Ref: E-036-2015/0 | Updated: May 17, 2017
T-cells Transduced with HLA A11 restricted CT-RCC HERV-E reactive TCR to Treat Patients with ccRCC
Ref: E-120-2016/0 | Updated: May 17, 2017
cGAP-PNA Multivalent Ligand Display at the Nanoscale
Ref: E-761-2013/0 | Updated: Apr 18, 2017
New T-cell Immunotherapy That Targets Aggressive Epithelial Tumors
Ref: E-153-2016/0 | Updated: Mar 3, 2017
Anti-CD133 Monoclonal Antibodies as Cancer Therapeutics
Ref: E-025-2015/0 | Updated: Feb 13, 2017
Griffithsin-based Anti-viral Therapeutics with Improved Stability and Solubility
Ref: E-065-2015/0 | Updated: Feb 13, 2017
Monoclonal Antibodies that Neutralize Norovirus
Ref: E-226-2011/0 | Updated: Jan 26, 2017
Use of Roseomonas Species to Treat Eczematous (Atopic Dermatitis) Skin Disease
Ref: E-099-2016/0 | Updated: Oct 27, 2016
Capsid-Free AAV Vectors for Gene Delivery and Their Use for Gene Therapy
Ref: E-241-2010/0 | Updated: Oct 12, 2016
Human Monoclonal Antibodies Targeting Glypican-2 in Neuroblastoma
Ref: E-211-2016/0 | Updated: Aug 8, 2016
Shark Antibodies that Target Tumor and Viral Antigens
Ref: E-113-2016/0 | Updated: Jul 7, 2016
Long Acting Therapeutic Conjugates with Evans Blue
Ref: E-143-2015/0 | Updated: Jun 27, 2016
Chimeric Antigen Receptors to CD276 for Treating Cancer
Ref: E-243-2015/0 | Updated: May 25, 2016
Tagged Form of Mut Enzyme and Its Use in Gene Therapy
Ref: E-090-2015/0 | Updated: Apr 18, 2016
Gene Therapy for Niemann-Pick Disease Type C
Ref: E-185-2014/0 | Updated: Apr 18, 2016
Fetal Hemoglobin Induction for Treating Sickle Cell Disease and Thalassemias
Ref: E-038-2016/0 | Updated: Dec 10, 2015
TRPC Knockout (KO) Mice and Mice with a Floxed Allele of TRPC Ion Channel Genes
Ref: E-071-2014/2 | Updated: Dec 8, 2015
Mice with a Floxed Allele of the alpha Subunit of the Heterotrimeric G Protein Go or Gi2
Ref: E-071-2014/0 | Updated: Dec 8, 2015
Mouse Model for Study of Diabetic Nephropathy and Role of Soluble Epoxide Hydrolase
Ref: E-292-2015/0 | Updated: May 24, 2016
Pseudomonas Exotoxin A with Modified Furin Cleavage Site
Ref: E-197-2015/0 | Updated: Sep 6, 2017
Anti-CD47 Antibodies for the Treatment of Cancer
Ref: E-263-2014/0 | Updated: Sep 10, 2015
A Novel Adeno-Associated Virus for Gene Therapy
Ref: E-175-2015/0 | Updated: Nov 1, 2017
Modified AAV5 Vectors for Enhanced Transduction and Reduced Antibody Neutralization
Ref: E-097-2015/0 | Updated: Nov 1, 2017
Novel Treatment for Anemia and Polycythemia: AVPR1B Molecules Modulating Erythropoiesis
Ref: E-619-2013/0 | Updated: Aug 6, 2015
Bispecific Chimeric Antigen Receptors to CD22 and CD19 for Treating Hematological Cancers
Ref: E-106-2015/0 | Updated: Feb 9, 2017
Device for Selective Partitioning of Frozen Cellular Products
Ref: E-173-2009/0 | Updated: Jun 29, 2015
A Novel Therapeutic Vector for Hemoglobin Disorders
Ref: E-165-2014/0 | Updated: Sep 21, 2015
A Novel T Cell Therapy Against Patient-Specific Cancer Mutations
Ref: E-229-2014/0 | Updated: Mar 29, 2017
A Novel, Personalized T Cell Therapy: T-Cell Receptor Engineered T Cells Targeting Tumor Specific Mutations
Ref: E-233-2014/0 | Updated: Mar 29, 2017
Novel Cancer Immunotherapy: HLA-A11 Restricted T Cell Receptor That Recognizes G12D Variant of Mutated KRAS
Ref: E-028-2015/0 | Updated: Oct 13, 2015
Novel Immunotherapy for Cancer Treatment: Chimeric Antigen Receptors Targeting CD70 Antigen
Ref: E-021-2015/0 | Updated: Oct 13, 2015
IFN Gamma for Reducing Adverse Ocular Side Effects of MEK-Inhibitor Therapy in Cancer
Ref: E-248-2012/0 | Updated: Jul 1, 2015
CXCR4 Reduction Leads to Enhancement of Engraftment of Hematopoietic Stem Cells
Ref: E-173-2014/0 | Updated: Jul 1, 2015
T Cell-Based Adoptive Transfer Immunotherapy for Polyomavirus-Associated Pathologies
Ref: E-166-2014/0 | Updated: Sep 12, 2017
89Zr-Oxine Complex for In Vivo PET Imaging of Labelled Cells and Associated Methods
Ref: E-080-2014/0 | Updated: Dec 2, 2015
T-cell Chimeric Receptors of TSLPR for Diagnosis and Immunotherapy of Cancer
Ref: E-008-2014/0 | Updated: Nov 20, 2014
The Use of Chimeric Antigen Receptor to Control HIV Infection
Ref: E-212-2014/0 | Updated: Sep 9, 2015
Photo-Controlled Removal of Targets In Vitro and In Vivo
Ref: E-209-2014/0 | Updated: Oct 9, 2014
Chimeric Receptors Targeting CD-19
Ref: E-042-2014/0 | Updated: Oct 28, 2014
A Novel Fusion Protein for Inhibiting HIV Budding
Ref: E-223-2014/0 | Updated: Sep 9, 2015
Monitoring the Effects of Sleep Deprivation Using Neuronal Avalanches
Ref: E-345-2013/0 | Updated: Aug 17, 2016
AAV-Vectors for Treatment of Glycogen Storage Disorders
Ref: E-552-2013/0 | Updated: Aug 6, 2014
Novel Anti-HIV Compounds (Peptides or Peptide Mimetics)
Ref: E-019-2014/0 | Updated: Sep 10, 2014
Cancer Immunotherapy Using Virus-like Particle Containing Alphavirus Replicons Coding for Therapeutic Proteins
Ref: E-050-2014/0 | Updated: Jun 27, 2016
Multifunctional RNA Nanoparticles as Therapeutic Agents
Ref: E-765-2013/0 | Updated: Nov 14, 2016
Nucleic Acid Nanoparticles for Triggering RNA Interference
Ref: E-156-2014/0 | Updated: Sep 9, 2015
Polypeptides and Methods for Enhancing and Balancing Monovalent or Multivalent Flavivirus Vaccines
Ref: E-275-2013/0 | Updated: Nov 30, 2016
Therapeutic for Glioblastoma Multiforme and Other Cancers
Ref: E-187-2012/0 | Updated: Feb 13, 2018
Novel Anti-HIV Proteins from Coral Reefs
Ref: E-295-2012/0 | Updated: May 20, 2015
Treatment of Chronic Kidney Disease with Synthetic Amphipathic Peptides
Ref: E-743-2013/0 | Updated: Jun 2, 2014
RNA Splicing Inhibitors to Treat Cancers
Ref: E-065-2014/0 | Updated: Jun 9, 2014
MDCK-based Reporter System for Detection of Influenza Viruses, Antiviral Drug Screening, and Analysis of Neutralizing Antibodies
Ref: E-185-2013/0 | Updated: May 15, 2014
Discrete Cross-Reactive Epitopes for Flavivirus Serological Diagnostics and Vaccines
Ref: E-333-2013/0 | Updated: May 15, 2014
Multi-specific Chimeric Antigen Receptors Against HIV
Ref: E-170-2013/0 | Updated: Oct 23, 2017
Treating or Inhibiting JC Polyomavirus Infection and JC Polyomavirus-Associated Progressive Multifocal Leukoencephalopathy
Ref: E-549-2013/0 | Updated: Apr 15, 2014
Role of Novel Hepatitis Delta Virus Variant in Sjogren’s Syndrome
Ref: E-736-2013/0 | Updated: Apr 14, 2014
Engineering Neural Stem Cells Using Homologous Recombination
Ref: E-762-2013/0 | Updated: Apr 14, 2014
Compositions for Modification of Genomic DNA and Exogenous Gene Expression
Ref: E-763-2013/0 | Updated: Apr 14, 2014
SCGB3A2 for Treatment of Cancer
Ref: E-286-2006/3 | Updated: Apr 15, 2014
Human Antibodies Against Middle East Respiratory Syndrome Coronavirus
Ref: E-002-2014/0 | Updated: Nov 28, 2017
Monoclonal Antibody Fragments for Targeting Therapeutics to Growth Plate Cartilage
Ref: E-003-2014/0 | Updated: Jun 29, 2017
Dengue Vaccines: Tools for Redirecting the Immune Response for Safe, Efficacious Dengue Vaccination
Ref: E-289-2013/0 | Updated: Mar 18, 2014
Human iPSC-Derived Mesodermal Precursor Cells and Differentiated Cells
Ref: E-342-2013/0 | Updated: Mar 18, 2014
Rabies Vaccine for the Oral Immunization of Domesticated Animals, Wildlife and Feral Animals
Ref: E-470-2013/0 | Updated: May 24, 2016
Use of Soluble CD27 as Potential Immunotherapy and a Diagnostic and Prognostic Serum Biomarker for Solid Tumors
Ref: E-005-2011/0 | Updated: Oct 23, 2017
Recombinant Sulfated HIV Envelope Protein and Methods for Making Protein
Ref: E-067-2012/0 | Updated: Apr 15, 2014
Methods for Amelioration and Treatment of Pathogen-associated Inflammatory Response
Ref: E-236-2013/0 | Updated: Feb 19, 2014
Peptide Sequences for Chlamydophila pneumoniae Vaccine and Serological Diagnosis
Ref: E-235-2013/0 | Updated: Feb 7, 2014
CD40 Ligand: Adjuvant for Enhanced Immune Response to Respiratory Syncytial Virus
Ref: E-233-2013/0 | Updated: Feb 6, 2014
Recombinant Polypeptides for Clinical Detection of Taenia solium and Diagnosis of Cysticercosis
Ref: E-230-2013/0 | Updated: Feb 6, 2014
Improved Personalized Cancer Immunotherapy: Rapid Selection of Tumor Reactive T Cells Based on Expression of Specific Cell Surface Markers from Peripheral Blood
Ref: E-085-2013/0 | Updated: Oct 13, 2015
Novel Immunocytokine for the Treatment of Cancer
Ref: E-118-2013/0 | Updated: Jan 31, 2014
Multivalent Immunogenic Peptides (Vaccines) for the Treatment of Prostate and Breast Cancer
Ref: E-047-2014/0 | Updated: Oct 23, 2017
Therapeutic, Bifunctional Janus Microparticles with Spatially Segregated Surface Proteins and Methods of Production
Ref: E-457-2013/1 | Updated: Jan 28, 2014
Vaccine Attenuation via Deoptimization of Synonymous Codons
Ref: E-328-2013/0 | Updated: Jan 28, 2014
Virus Replicon Particles as Rift Valley Fever Vaccines
Ref: E-272-2013/0 | Updated: Aug 8, 2016
Select M. tuberculosis Peptides as Mucosal Vaccines Against Pulmonary Tuberculosis
Ref: E-192-2013/0 | Updated: Jan 27, 2014
Exposure and Activity Detection Assays for Anthrax Lethal Factor and Lethal Toxin
Ref: E-196-2013/0 | Updated: Mar 3, 2017
Multi-Antigenic Peptide(s) Vaccine and Immunogen for Conferring Streptococcus pneumoniae Immunity
Ref: E-248-2013/1 | Updated: Jan 27, 2014
Virus Microneutralization Assay Data Analysis for Vaccine Development, Enhancement and Efficacy Improvement
Ref: E-262-2013/0 | Updated: Jan 27, 2014
Immunogenic Hepatitis E Virus Polypeptides for Vaccine and Diagnostics Development
Ref: E-152-2013/0 | Updated: Jan 20, 2014
Improved Therapeutic Immunotoxins
Ref: E-771-2013/0 | Updated: Sep 6, 2017
Methods of Treating or Preventing Pruritis (Itch)
Ref: E-485-2013/0 | Updated: Jan 16, 2014
Respiratory Syncytial Virus Immunogens for Vaccine and Therapeutics Development
Ref: E-197-2013/0 | Updated: Jan 16, 2014
Novel Primate T-cell Lymphotropic Viruses (HTLV, STLV) for Development of Diagnostics, Therapeutics, Research Tools, and Vaccines
Ref: E-281-2013/0 | Updated: May 24, 2016
Diisocyanate Specific Monoclonal Antibodies for Occupational and Environmental Monitoring of Polyurethane Production Exposure-related Asthma and Allergy and Clinical Diagnosis
Ref: E-189-2013/0 | Updated: Jan 23, 2014
Chimeric Antigen Receptors to CD276 (B7-H3) for Treatment of Cancer
Ref: E-104-2013/0 | Updated: Nov 28, 2017
Human Rotavirus Strains and Vaccines for Neonatal Childhood Protection
Ref: E-150-2013/0 | Updated: Feb 13, 2014
Novel Epitopes of Bacillus anthracis Lethal Factor for Development of Diagnostics and Therapeutics
Ref: E-210-2013/0 | Updated: Mar 3, 2017
Chimeric Antigen Receptors to ALK for Treating Neuroblastoma and Other Solid Tumors
Ref: E-007-2014/0 | Updated: Jan 18, 2018
Diagnostics, Vaccines, and Delivery-Vehicles Related to Novel Phlebovirus
Ref: E-269-2013/0 | Updated: Dec 4, 2013
Intranasal Nebulizer with Disposable Drug Cartridge for Improved Delivery of Vaccines and Therapeutics
Ref: E-308-2013/0 | Updated: Apr 11, 2014


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